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DcR2 antibody (AA 1-210) (PE)

Name: DcR2 antibody (AA 1-210) (PE)
Brand: antibodies-online
SKU: ABIN457378
Price: 826.86 USD
Availability: InStock

TNFRSF10D Reactivity: Human FACS Host: Mouse Monoclonal TRAIL-R4-01 PE

Separation of cells stained using anti-human CD264 (TRAIL-R4-01) PE antibody (concentration in sample 1,67 μg/mL, red-filled) from cells stained using mouse IgG1 isotype control (MOPC-21) PE antibody (concentration in sample 1,67 μg/mL, same as CD264 PE concentration, black-dashed) in flow cytometry analysis (surface staining) of suspension of TRAIL-R4 transfected HEK-293 cells. (DcR2 antibody (AA 1-210) (PE))

FACS

Surface staining of CD264-transfectants using anti-CD264 (TRAIL-R4-01) PE. (DcR2 antibody (AA 1-210) (PE))

FACS

2 images

Catalog No. ABIN457378

Datasheet as PDF

Target See all DcR2 (TNFRSF10D) Antibodies

DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
Binding Specificity
5

5

5

4

4

4

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1
AA 1-210
Reactivity
73

6

5
Human
Host
58

15
Mouse
Compatible Secondaries
Clonality
57

16
Monoclonal
Conjugate
35

5

5

4

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This DcR2 antibody is conjugated to PE
Application
50

30

17

11

6

5

3

3

2

1

1
Flow Cytometry (FACS)

Purpose

Anti-Hu CD264 PE

Specificity

The antibody TRAIL-R4-01 reacts with an extracellular epitope of TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells.

Cross-Reactivity (Details)

Human

Purification

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen

TRAIL-R4 (aa 1-210) - hIgGhc fusion protein

Clone

TRAIL-R4-01

Isotype

IgG1

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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 56-211) antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibody
TNFRSF10D Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 1-210) antibody (FITC)
TNFRSF10D Reactivity: Human FACS Host: Mouse Monoclonal TRAIL-R4-01 FITC

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibody
TNFRSF10D Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 1-210) antibody (APC)
TNFRSF10D Reactivity: Human FACS Host: Mouse Monoclonal TRAIL-R4-01 APC

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 252-278) antibody
TNFRSF10D Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB24080 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 249-263) antibody
TNFRSF10D Reactivity: Human, Mouse, Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 257-386) antibody
TNFRSF10D Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 249-263), (Intracellular) antibody
TNFRSF10D Reactivity: Human, Mouse, Rat WB, IF, EIA Host: Rabbit Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibody
TNFRSF10D Reactivity: Human WB, IP Host: Mouse Monoclonal B-P30 unconjugated

Application Notes

Flow cytometry: Recommended dilution: 1-4 μg/mL

Restrictions

For Research Use only
Concentration

0.1 mg/mL

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Do not freeze.
Avoid prolonged exposure to light.

Storage

4 °C

Storage Comment

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Target

DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))

Alternative Name

CD264 (TNFRSF10D Products)

Background

TNF receptor superfamily member 10d,TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs to receptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4).,TNFRSF10D, DcR2, TRUNDD, TRAILR4

Gene ID

8793

UniProt

Q9UBN6

Pathways

Apoptosis