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DcR2 Products

(Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008].

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Featured DcR2 Categories

DcR2 Antibodies

High quality antibodies with extensive validation data.

DcR2 ELISA Kits

Reliable ELISA kits for a wide range of species.

DcR2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DcR2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (4)
Cat. No. ABIN5684100
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (4)
Cat. No. ABIN5684099
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application FACS
Validations
  • (3)
Cat. No. ABIN457356
Quantity 0.1 mg
Datasheet Datasheet

Recommended DcR2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973655
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1117546
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1117674
Quantity 96 tests
Datasheet Datasheet

Recommended DcR2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7275782
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275781
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
  • (2)
Cat. No. ABIN3071467
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our DcR2 products

Willms, Schittek, Rahn, Sosna, Mert, Adam, Trauzold: "Impact of p53 status on TRAIL-mediated apoptotic and non-apoptotic signaling in cancer cells." in: PLoS ONE, Vol. 14, Issue 4, pp. e0214847, (2019) (PubMed).

Jo, Lee, Lee, Park, Park, Choi, Hong, Kim: "Combination therapy with c-met inhibitor and TRAIL enhances apoptosis in dedifferentiated liposarcoma patient-derived cells." in: BMC cancer, Vol. 19, Issue 1, pp. 496, (2019) (PubMed).

Fakiruddin, Lim, Nordin, Rosli, Zakaria, Abdullah: "Targeting of CD133+ Cancer Stem Cells by Mesenchymal Stem Cell Expressing TRAIL Reveals a Prospective Role of Apoptotic Gene Regulation in Non-Small Cell Lung Cancer." in: Cancers, Vol. 11, Issue 9, (2019) (PubMed).

Shlyakhtina, Pavet, Gronemeyer: "Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells." in: Cell death & disease, Vol. 8, Issue 8, pp. e3025, (2018) (PubMed).

Danish, Imig, Allgöwer, Scheurich, Pollak: "Bcl-2-mediated control of TRAIL-induced apoptotic response in the non-small lung cancer cell line NCI-H460 is effective at late caspase processing steps." in: PLoS ONE, Vol. 13, Issue 6, pp. e0198203, (2018) (PubMed).

Singh, Otano, Rombouts, Singh, Peppa, Gill, Böttcher, Kennedy, Oben, Pinzani, Walczak, Fusai, Rosenberg, Maini: "TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis." in: Scientific reports, Vol. 7, Issue 1, pp. 5514, (2017) (PubMed).

Jaworska, Szliszka: "Targeting Apoptotic Activity Against Prostate Cancer Stem Cells." in: International journal of molecular sciences, Vol. 18, Issue 8, (2017) (PubMed).

Madsen, Russell, Tucker, Glowacki, Bunnell, OConnor: "Decoy TRAIL receptor CD264: a cell surface marker of cellular aging for human bone marrow-derived mesenchymal stem cells." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 201, (2017) (PubMed).

Hartwig, Montinaro, von Karstedt, Sevko, Surinova, Chakravarthy, Taraborrelli, Draber, Lafont, Arce Vargas, El-Bahrawy, Quezada, Walczak: "The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2." in: Molecular cell, Vol. 65, Issue 4, pp. 730-742.e5, (2017) (PubMed).

Todorova, Bock, Chang: "Poly(ADP-ribose) polymerase-13 and RNA regulation in immunity and cancer." in: Trends in molecular medicine, Vol. 21, Issue 6, pp. 373-84, (2015) (PubMed).

Synonyms and alternative names related to DcR2

TNF receptor superfamily member 10d (TNFRSF10D), tumor necrosis factor receptor superfamily member 10D (LOC716901), CD264, DCR2, TNFRSF10D, TRAIL-R4, TRAILR4, TRUNDD

Protein level used designations for DcR2

  • tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
  • TNF receptor-related receptor for TRAIL
  • TNF-related apoptosis-inducing ligand receptor 4
  • TRAIL receptor 4
  • TRAIL receptor with a truncated death domain
  • decoy receptor 2
  • tumor necrosis factor receptor superfamily member 10D
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