CD40 antibody (AA 258-277)

Catalog No. ABIN457484

The Rabbit Polyclonal anti-CD40 antibody is suitable to detect CD40 in samples from Human, Mouse and Horse. It has been validated for WB, IHC and IHC (p).

Quick Overview for CD40 antibody (AA 258-277) (ABIN457484)

Target: CD40

Reactivity: Human, Mouse, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD40 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CD40 Antibody

Binding Specificity: AA 258-277

Specificity: Detects an ~45 kD protein, corresponding to the apparent molecular mass of CD40 on SDS-PAGE immunoblots, in samples from human, mouse, rat, bovine, canine, guinea pig, hamster, monkey, pig, rabbit and sheep origins.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Elephant, Horse (100%) Marmoset, Rat, Porcine, Bat, Dog, Rabbit (95%) Panda, Bovine (90%) Hamster (85%) Opossum (80%).

Immunogen: A 20 residue synthetic peptide CQPVTQEDGKESRISVQERQ based on the human CD40 (residues 258-277) was synthesized and the peptide coupled to KLH. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Elephant, Horse (100%), Marmoset, Rat, Porcine, Bat, Dog, Rabbit (95%), Panda, Bovine (90%), Hamster (85%), Opossum (80%).

Type of Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for CD40

Target: CD40

Alternative Name: CD40

Background: Name/Gene ID: CD40
Family: TNF Receptor

Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5

Gene ID: 958

Pathways: NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints