LASS3 antibody

Catalog No. ABIN4620355

Product Details anti-LASS3 Antibody

Target: LASS3 (CERS3) (Ceramide Synthase 3 (CERS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LASS3 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects Lass3. Expression of Lass3 appears to be solely limited to the testis.

Purification: Affinity chromatography

Immunogen: Synthetic peptide derived from human LASS3 protein

Application Details

Application Notes: Western blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Target Details for LASS3

Target: LASS3 (CERS3) (Ceramide Synthase 3 (CERS3))

Alternative Name: LASS3 (CERS3 Products)

Background: LASS3 (Longevity Assurance homolog 3) is a member of a highly conserved family of proteins from yeast to humans which are involved in the synthesis of ceramide. Overproduction of LASS3 appears to results in increases in several ceramide species, with some preference toward those having middle to long chain fatty acid acyl-CoAs. Also appears to have (dihydro)ceramide synthesis activity. LASS3 expression appears to be limited almost solely to the testis.Synonyms: LAG1 longevity assurance homolog 3

Gene ID: 204219

NCBI Accession: NP_849164

UniProt: Q8IU89