DEGS1 antibody

Catalog No. ABIN4620377

The Rabbit Polyclonal anti-DEGS1 antibody is suitable to detect DEGS1 in samples from Human, Mouse and Rat. It has been validated for WB and IHC (p).

Quick Overview for DEGS1 antibody (ABIN4620377)

Target: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEGS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DEGS1 Antibody

Specificity: This antibody detects Degenerative Spermatocyte Homolog 1.

Purification: Affinity chromatography

Immunogen: Synthetic peptide derived from the human DEGS1 protein

Isotype: IgG

Application Details

Application Notes: Western Blot (1: 400 starting dilution). Positive control: Placenta.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0.08 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Target Details for DEGS1

Target: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Alternative Name: DEGS1

Background: The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.Synonyms: DES1, Degenerative spermatocyte homolog 1, MIG15, MLD, Membrane lipid desaturase, Migration-inducing gene 15 protein, Sphingolipid delta(4)-desaturase DES1

Gene ID: 8560

NCBI Accession: NP_003667

UniProt: O15121