CD66acd antibody

Catalog No. ABIN472061

The Rat Monoclonal anti-CD66acd antibody has been validated for FACS, IHC (fro) and IHC. It is suitable to detect CD66acd in samples from Human and Rhesus Monkey.

Quick Overview for CD66acd antibody (ABIN472061)

Target: CD66acd (CEACAM1/3/6) (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/3/6 (CEACAM1/3/6))

Reactivity: Human, Rhesus Monkey

Host: Rat

Clonality: Monoclonal

Conjugate: This CD66acd antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC)

Clone: YTH71-3

Product Details anti-CD66acd Antibody

Specificity: Recognizes 3 members of the human CD66 family, namely CD66a, also known as Carcinoembryonic antigen-related cell adhesion molecule 1, Biliary glycoprotein 1 or CEACAM1. Clone YTH71.3 also recognizes CD66c, known as Carcinoembryonic antigen-related cell adhesion molecule 6 or Non-specific cross-reacting antigen. In addition the clone also recognizes CD66d which in turn is also known as Carcinoembryonic antigen-related cell adhesion molecule 3 or CGM1. CD66 family members are single pass, type 1 membrane glycoproteins bearing a single domain and a varying number of domains. Clone YTH71.3 recognizes epitopes in the of these CD66 family members. CD66 members are expressed by human neutrophils and cells of the colon where it is down regulated in some cases of colon carcinoma. CD66a is also expressed in the human alveolar adenocarcinoma cell line A549 and may play a role in Moraxella catarrhalis induced apoptosis of pulmonary epithelial cells in diseases including COPD and emphysema.

Purification: Affinity purified

Immunogen: Human lymphocytes.

Type of Immunogen: Cells

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo, IHC, IHC-Fr

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1 x 10^6 cells in 100 μL. Method sheets are available on request.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD66acd

Target: CD66acd (CEACAM1/3/6) (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/3/6 (CEACAM1/3/6))

Alternative Name: CD66acd