MHC Class I H-2Db (Chain alpha 3), (Domain alpha 3) antibody

Catalog No. ABIN479215

This Mouse Monoclonal antibody specifically detects in FACS, CyTox, IHC and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for MHC Class I H-2Db (Chain alpha 3), (Domain alpha 3) antibody (ABIN479215)

Target: MHC Class I H-2Db

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS), Cytotoxicity Test (CyTox), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 28-14-8

Product Details

Binding Specificity: Chain alpha 3, Domain alpha 3

Specificity: Recognizes an epitope in the alpha3 domain of H-2Db. It cross-reacts with the alpha3 domain of H-2Ld, but not Kd or Dd, and with H-2Dq and/or Lq. Has been shown to block H-2Ld-specific and H-2Ld-restricted antigen-specific lysis of target cells by cytotoxic T lymphocytes, but it does not block recognition of H-2Ld-positive target cells by Ly-6G2-positive NK cells.

Purification: Purified

Immunogen: C3H. SW mouse splenocytes.

Type of Immunogen: Cells

Isotype: IgG2a kappa

Application Details

Application Notes: Approved: Ctox, Flo, IHC, IHC-Fr

Usage: Flow cytometry. Immunohistochemistry (frozen tissue sections). Complement-mediated cytotoxicity. Flow Cytometry: 1 μg/1 x10⁶.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 100 mM borate buffered saline,  pH 8.0. No preservatives or amine-containing buffer salts added.

Preservative: Without preservative

Target Details

Target: MHC Class I H-2Db