Progesterone 17-OH antibody

Catalog No. ABIN487526

This Sheep Polyclonal antibody specifically detects Progesterone 17-OH in EIA.

Quick Overview for Progesterone 17-OH antibody (ABIN487526)

Target: Progesterone 17-OH

Reactivity: Please inquire

Host: Sheep

Clonality: Polyclonal

Conjugate: This Progesterone 17-OH antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-Progesterone 17-OH Antibody

Purification: Ig Fraction

Immunogen: 17-alpha-OH-Progesterone-BTG

Isotype: IgG

Application Details

Application Notes: ELISA: 0.31 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 8.61mg/mL (U.V. abs at 280nm)

Buffer: 20 mM Phosphate, 150 mM Sodium Chloride, pH 7.2 containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for Progesterone 17-OH

Target: Progesterone 17-OH

Target Type: Hormone

Background: 17-Hydroxyprogesterone (17-OH progesterone or 17OHP) is a C-21 steroid hormone produced during the synthesis of glucocorticoids and sex steroids. It is derived from progesterone via 17-hydroxylase, a P450c17 enzyme, or from 17-hydroxypregnenolone via 3-beta-hydroxysteroid dehydrogenase / Delta 5-4 isomerase. 17-Hydroxyprogesterone is a natural progestogen, and in pregnancy increases in the third trimester primarily due to fetal adrenal production. This hormone is primarily produced in the adrenal glands and to some degree in the gonads, specifically the corpus luteum of the ovary. Hydroxyprogesterone has been used for recurrent miscarriage and various menstrual disorders. Women who have had a spontaneous preterm delivery are at greatly increased risk for preterm delivery in subsequent pregnancies. The results of several small trials have suggested that hydroxyprogesterone may reduce the risk of preterm delivery.Synonyms: 17-Hydroxyprogesterone, 17-alpha-Hydroxy-Progesterone, 17OHP