CR
Reactivity: Various Species
ELISA, IA, AP
Host: Sheep
Polyclonal
unconjugated
Application Notes
ELISA: 2 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
6.47 mg/mL (U.V. abs at 280nm)
Buffer
20 mM Phosphate, 150 mM Sodium Chloride, pH 7.2, 0.09 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Target
Creatinine (CR)
Alternative Name
Creatinine
Target Type
Amino Acid
Background
Creatinine is present in all body secretions and is a by-product of muscle metabolism, formed by the spontaneous and irreversible conversion of creatine and creatine phosphate. The formation of creatinine is proportional to total muscle mass and body weight. The production rate shows minimal daily variations, unless the muscle mass changes, with 2?% of whole body creatinine being transformed every 24 hours. Since creatinine is excreted at a relatively constant rate by the kidneys, measurement of urinary creatinine can indicate if the urinary concentration has been adjusted by in vivo or in vitro dilution. The level of creatinine in the blood increases as kidney disease progresses.Synonyms: 2-amino-1-methyl-5H-imidazol-4-one