Imipramine antibody

Catalog No. ABIN487706

This Sheep Polyclonal antibody specifically detects Imipramine in EIA. It exhibits reactivity toward .

Quick Overview for Imipramine antibody (ABIN487706)

Target: Imipramine

Host: Sheep

Clonality: Polyclonal

Conjugate: This Imipramine antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-Imipramine Antibody

Purification: Ig Fraction

Immunogen: Imipramine-BTG

Isotype: IgG

Application Details

Application Notes: ELISA: 0.625 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 6.38 mg/mL (U.V.abs at 280nm)

Buffer: 20 mM Phosphate, 150 mM Sodium Chloride, pH 7.2 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at-20 °C.

Target Details for Imipramine

Target: Imipramine

Target Type: Chemical

Background: Tricyclic antidepressants contain a characteristic three ringed nucleus structure. They act primarily as serotoninnorepinephrine reuptake inhibitors. Tricyclic antidepressants are mainly used as antidepressants, but have also been for the treatment of anxiety disorders and attention hyperactivity disorder and as an adjunct to certain analgesics to treat chronic pain. In many treatments they have been replaced by other compounds with fewer sideeffects. Tricyclic antidepressants are not considered addictive and have a low abuse potential, but suddenly discontinuing treatment may results in discontinuation syndrome and overdose is a main cause of death from prescription drugs. They have significant cardiovascular and neurological toxicity. Monitoring of TCA levels can help determine toxicity, monitor compliance and establish individual target concentrations. Imipramine is a member of the family of tricyclic antidepressants. Its clinical effect is hypothesized as being due to potentiation of adrenergic synapses by blocking uptake of norepinephrine at nerve endings. Imipramine is a very powerful antidepressant and is converted to desipramine in the body.Synonyms: Antideprin, Berkomine, Cristalia, Melipramine, Prazepine, Sermonil, Tricyclic Antidepressant