RETNLB antibody (Internal Region)

Catalog No. ABIN487999

This Goat Polyclonal antibody specifically detects RETNLB in EIA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for RETNLB antibody (Internal Region) (ABIN487999)

Target: RETNLB (Resistin Like beta (RETNLB))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This RETNLB antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RETNLB Antibody

Binding Specificity: Internal Region

Sequence: c-DSVMDKKIKD VLNS

Specificity: This antibody recognizes Human RELM beta. Other species not tested.

Purification: Affinity Chromatography

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_115968.1.

Application Details

Application Notes: Peptide ELISA: 1/128000. Immunohistochemistry on paraffin sections: Human Colon shows textured staning ofcytoplasm in enterocytes. Recommended concentration: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for RETNLB

Target: RETNLB (Resistin Like beta (RETNLB))

Alternative Name: RELM beta

Background: RELM beta, is a secreted protein, a probable hormone, expressed only in the gastrointestinal tract, particularly the colon. The biological functions of RELM beta and its molecular targets, are not fully known but, it has been suggested that it plays a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver. Interestingly the molecular structure of RELM beta is highly homologous to that of the adipose-derived cytokine Resistin and RELM alpha.Synonyms: CCRG, Colon and small intestine-specific cysteine-rich protein, Colon carcinoma-related gene protein, Cysteine-rich secreted protein A12-alpha-like 1, Cysteine-rich secreted protein FIZZ2, FIZZ2, HXCP2, RELM-beta RETNLB, RELMbeta, RETNL2, Resistin-like beta

Gene ID: 84666

NCBI Accession: NP_115968

UniProt: Q9BQ08

Pathways: Hormone Activity