ADAMTS13 antibody (AA 299-488)

Catalog No. ABIN4886425

This Rabbit Polyclonal antibody specifically detects ADAMTS13 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ADAMTS13 antibody (AA 299-488) (ABIN4886425)

Target: ADAMTS13 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAMTS13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADAMTS13 Antibody

Binding Specificity: AA 299-488

Purpose: Anti-ADAMTS13 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-ADAMTS13 Antibody (ABIN4886425). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human ADAMTS13 recombinant protein (Position: A299-R488). Human ADAMTS13 shares 85.2% amino acid (aa) sequence identity with mouse ADAMTS13.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
ELISA(Cap) , 0.1-0.5 μg/mL, Human, -

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for ADAMTS13

Target: ADAMTS13 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))

Alternative Name: ADAMTS13

Background:

Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 13,ADAM-TS 13,ADAM-TS13,ADAMTS-13,3.4.24.87,von Willebrand factor-cleaving protease,vWF-CP,vWF-cleaving protease,ADAMTS13,C9orf8,UNQ6102/PRO20085,

Tissue Specificity: Plasma. Expressed primarily in liver. .

Background: ADAMTS13 (a disintegrin and metalloproteinase with athrombospondin type 1 motif, member 13), also known as VWFCP, is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting. It is secreted in blood and degrades large vWf multimers, decreasing their activity. This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. This gene is mapped to 9q34.

Molecular Weight: 154 kDa

Gene ID: 11093