CCDC6 antibody (N-Term)

Catalog No. ABIN4886506

This Rabbit Polyclonal antibody specifically detects CCDC6 in WB, IF, FACS and ICC. It exhibits reactivity toward Human and Rat.

Quick Overview for CCDC6 antibody (N-Term) (ABIN4886506)

Target: CCDC6 (Coiled-Coil Domain Containing 6 (CCDC6))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Product Details anti-CCDC6 Antibody

Binding Specificity: AA 156-198, N-Term

Purpose: Anti-CCDC6 Antibody Picoband®

Sequence: KAELEQHLEQ EQEFQVNKLM KKIKKLENDT ISKQLTLEQL RR

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-CCDC6 Antibody Picoband® (ABIN4886506). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CCDC6, identical to the related mouse sequence.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Anne-Spence M, Falk CT, Neiswanger K, Field LL, Marazita ML, Allen FH, Siervogel RM, Roche AF, Crandall BF, Sparkes RS (Sep 1984). "Estimating the recombination frequency for the PTC-Kell linkage". Human Genetics 67(2): 183-6. 2. Grieco M, Cerrato A, Santoro M, Fusco A, Melillo RM, Vecchio G (Sep 1994). "Cloning and characterization of H4 (D10S170), a gene involved in RET rearrangements in vivo". Oncogene 9 (9): 2531-5.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for CCDC6

Target: CCDC6 (Coiled-Coil Domain Containing 6 (CCDC6))

Alternative Name: CCDC6

Background:

Synonyms: Coiled-coil domain-containing protein 6,Papillary thyroid carcinoma-encoded protein,Protein H4,CCDC6,D10S170, TST1,

Tissue Specificity: Ubiquitously expressed.

Background: Coiled-coil domain-containing protein 6 is a protein that in humans is encoded by the CCDC6 gene. This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.

Molecular Weight: 66 kDa

Gene ID: 8030

UniProt: Q16204