FHL3 antibody (N-Term)

Catalog No. ABIN4886590

This Rabbit Polyclonal antibody specifically detects FHL3 in WB. It exhibits reactivity toward Human and Rat.

Quick Overview for FHL3 antibody (N-Term) (ABIN4886590)

Target: FHL3 (Four and A Half LIM Domains 3 (FHL3))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FHL3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FHL3 Antibody

Binding Specificity: AA 41-84, N-Term

Purpose: Anti-FHL3 Antibody

Sequence: AECQQLIGHD SRELFYEDRH FHEGCFRCCR CQRSLADEPF TCQD

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-FHL3 Antibody (ABIN4886590). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human FHL3, identical to the related mouse sequence.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Rat

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for FHL3

Target: FHL3 (Four and A Half LIM Domains 3 (FHL3))

Alternative Name: FHL3

Background:

Synonyms: Four and a half LIM domains protein 3,FHL-3,Skeletal muscle LIM-protein 2,SLIM-2,FHL3,SLIM2,

Tissue Specificity: Expressed only in skeletal muscle.

Background: Four and a half LIM domains protein 3 is a protein that in humans is encoded by the FHL3 gene. The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 31 kDa

Gene ID: 2275

UniProt: Q13643