HNRNPL antibody (C-Term)

Catalog No. ABIN4886624

Product Details anti-HNRNPL Antibody

Target: HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Binding Specificity: AA 546-571, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPL antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Heterogeneous nuclear ribonucleoprotein L (HNRNPL) detection. Tested with WB in Human.

Sequence: LLEWESKSDA LETLGFLNHY QMKNPN

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Heterogeneous nuclear ribonucleoprotein L (HNRNPL) detection. Tested with WB in Human.
Gene Name: heterogeneous nuclear ribonucleoprotein L
Protein Name: Heterogeneous nuclear ribonucleoprotein L

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human HnRNP L (546-571aa LLEWESKSDALETLGFLNHYQMKNPN), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for HNRNPL

Target: HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Alternative Name: HNRNPL (HNRNPL Products)

Synonyms: HNRPL antibody, hnRNP-L antibody, zgc:55429 antibody, HNRNPL antibody, hnrpl antibody, C79783 antibody, D830027H13Rik antibody, Hnrpl antibody, hnrnp-L antibody, heterogeneous nuclear ribonucleoprotein L antibody, HNRNPL antibody, hnrpl antibody, hnrnpl antibody, Hnrnpl antibody

Background: Heterogeneous nuclear ribonucleoprotein L is a protein that in humans is encoded by the HNRNPL gene. Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. HNRNPL is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. It is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: hnRNP L | hnRNP-L | Hnrnpl | hnRPL | P/OKcl.14 | P14866

Gene ID: 3191

UniProt: P14866