ITLN1/Omentin antibody (N-Term)

Catalog No. ABIN4886644

This Rabbit Polyclonal antibody specifically detects ITLN1/Omentin in WB, IHC, ICC, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for ITLN1/Omentin antibody (N-Term) (ABIN4886644)

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITLN1/Omentin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-ITLN1/Omentin Antibody

Binding Specificity: AA 19-59, N-Term

Purpose: Anti-ITLN1 Antibody Picoband®

Sequence: TDEANTYFKE WTCSSSPSLP RSCKEIKDEC PSAFDGLYFL R

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-ITLN1 Antibody Picoband® (ABIN4886644). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ITLN1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. "Entrez Gene: ITLN1 intelectin 1 (galactofuranose binding)". 2. Lee JK, Schnee J, Pang M, Wolfert M, Baum LG, Moremen KW, Pierce M (Feb 2001). "Human homologs of the Xenopus oocyte cortical granule lectin XL35". Glycobiology 11 (1): 65-73. 3. Tsuji S, Uehori J, Matsumoto M, Suzuki Y, Matsuhisa A, Toyoshima K, Seya T (Jun 2001). "Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall". J Biol Chem 276 (26): 23456-63.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for ITLN1/Omentin

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Alternative Name: ITLN1

Background:

Synonyms: Intelectin-1,ITLN-1,Endothelial lectin HL-1,Galactofuranose-binding lectin,Intestinal lactoferrin receptor,Omentin,ITLN1,INTL, ITLN, LFR,UNQ640/PRO1270,

Tissue Specificity: Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus. .

Background: Intelectin-1, also known as omentin, is an intelectin encoded in humans by the ITLN1 gene. This gene is mapped to chromosome 1q21.3-q22 by genomic sequence analysis. It is expressed on multiple cell types and appears to participate in insulin signaling and microbe recognition. Intelectin-1 functions both as a receptor for bacterial arabinogalactans and for lactoferrin. Having conserved ligand binding site residues, both human and mouse intelectin-1 bind the exocyclic vicinal diol of carbohydrate ligands such as galactofuranose.

Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Molecular Weight: 43 kDa

Gene ID: 55600