ORM1 antibody (AA 19-201)

Catalog No. ABIN4886686

This Rabbit Polyclonal antibody specifically detects ORM1 in WB, IHC and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ORM1 antibody (AA 19-201) (ABIN4886686)

Target: ORM1 (Orosomucoid 1 (ORM1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-ORM1 Antibody

Binding Specificity: AA 19-201

Purpose: Anti-Alpha 1 Acid Glycoprotein/ORM1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Alpha 1 Acid Glycoprotein/ORM1 Antibody Picoband® (ABIN4886686). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human ORM1 recombinant protein (Position: Q19-S201). Human ORM1 shares 47.5% and 48.1% amino acid (aa) sequence identity with mouse and rat ORM1, respectively.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: ORM1 orosomucoid 1". 2. Boncela, J, Papiewska I, Fijalkowska I, Walkowiak B, Cierniewski C S (Sep 2001). "Acute phase protein alpha 1-acid glycoprotein interacts with plasminogen activator inhibitor type 1 and stabilizes its inhibitory activity". J. Biol. Chem. (United States) 276 (38): 35305-11. 3. Eiberg, H., Mohr, J., Nielsen, L. S. Linkage of orosomucoid (ORM) to ABO and AK1. (Abstract) Cytogenet. Cell Genet. 32: 272 only, 1982.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for ORM1

Target: ORM1 (Orosomucoid 1 (ORM1))

Alternative Name: ORM1

Background:

Synonyms: Alpha-1-acid glycoprotein 1,AGP 1,Orosomucoid-1,OMD 1,ORM1,AGP1,

Tissue Specificity: Expressed by the liver and secreted in plasma.

Background: Alpha-1-acid glycoprotein 1 is a protein that in humans is encoded by the ORM1 gene. The structural gene for orosomucoid (ORM1) is assigned to the end of the long arm of chromosome 9 by demonstration of linkage to ABO and AK1. This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined, however, it may be involved in aspects of immunosuppression.

Molecular Weight: 40-47 kDa

Gene ID: 5004

UniProt: P02763

Pathways: Response to Growth Hormone Stimulus