RPSA/Laminin Receptor antibody (AA 2-138)

Catalog No. ABIN4886715

This anti-RPSA/Laminin Receptor antibody is a Rabbit Polyclonal antibody detecting RPSA/Laminin Receptor in WB, IHC, IF, FACS, ICC and IHC (fro). Suitable for Human.

Quick Overview for RPSA/Laminin Receptor antibody (AA 2-138) (ABIN4886715)

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPSA/Laminin Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RPSA/Laminin Receptor Antibody

Binding Specificity: AA 2-138

Purpose: Anti-67kDa Laminin Receptor/RPSA Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-67kDa Laminin Receptor/RPSA Antibody Picoband® (ABIN4886715). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human RPSA recombinant protein (Position: S2-S138). Human RPSA shares 100% and 99.3% amino acid (aa) sequence identity with mouse and rat RPSA, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human1. "Entrez Gene: RPSA ribosomal protein SA". 2. Jackers P, Minoletti F, Belotti D, Clausse N, Sozzi G, Sobel ME, Castronovo V (Sep 1996). "Isolation from a multigene family of the active human gene of the metastasis-associated multifunctional protein 37LRP/p40 at chromosome 3p21.3". Oncogene 13 (3): 495-503. 3. Satoh K, Narumi K, Sakai T, Abe T, Kikuchi T, Matsushima K, Sindoh S, Motomiya M (Jul 1992). "Cloning of 67- kDa laminin receptor cDNA and gene expression in normal and malignant cell lines of the human lung". Cancer Lett 62 (3): 199-203.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for RPSA/Laminin Receptor

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Alternative Name: RPSA

Background:

Synonyms: 40S ribosomal protein SA ,37 kDa laminin receptor precursor ,37LRP ,37/67 kDa laminin receptor ,LRP/LR ,67 kDa laminin receptor ,67LR ,Colon carcinoma laminin-binding protein,Laminin receptor 1 ,LamR ,Laminin-binding protein precursor p40 ,LBP/p40 ,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,RPSA ,LAMBR, LAMR1,

Tissue Specificity: Expressed in a wide variety of actively proliferating cells and tumor tissues.

Background: Adipose differentiation-related protein, also known as perilipin 2 (PLIN2), ADRP or adipophilin, is a protein which in humans is encoded by the ADFP gene. The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 40 kDa

Gene ID: 3921

UniProt: P08865

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly