TREX2 antibody (AA 69-279)

Catalog No. ABIN4886755

Product Details anti-TREX2 Antibody

Target: TREX2 (Trex2) (three Prime Repair Exonuclease 2 (Trex2))

Binding Specificity: AA 69-279

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TREX2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Anti-TREX2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TREX2 Antibody Picoband® (ABIN4886755). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human TREX2 recombinant protein (Position: E69-A279). Human TREX2 shares 88.6% amino acid (aa) sequence identity with mouse TREX2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: TREX2 three prime repair exonuclease 2". 2. Mazur DJ, Perrino FW (Aug 1999). "Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases". J Biol Chem 274 (28): 19655-60.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for TREX2

Target: TREX2 (Trex2) (three Prime Repair Exonuclease 2 (Trex2))

Alternative Name: TREX2 (Trex2 Products)

Background:

Synonyms: Three prime repair exonuclease 2,3.1.11.2,3'-5' exonuclease TREX2,TREX2,

Tissue Specificity: Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus. .

Background: Three prime repair exonuclease 2 is an enzyme that in humans is encoded by the TREX2 gene. By genomic sequence analysis, the TREX2 gene is mapped to chromosome Xq28. This gene encodes a protein with 3' exonuclease activity. Enzymes with this activity are involved in DNA replication, repair, and recombination. Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have intrinsic exonuclease activity.

Molecular Weight: 37 kDa

Gene ID: 11219