VAMP7 antibody (AA 24-190)

Catalog No. ABIN4886758

This Rabbit Polyclonal antibody specifically detects VAMP7 in WB. It exhibits reactivity toward Human and Rat.

Quick Overview for VAMP7 antibody (AA 24-190) (ABIN4886758)

Target: VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAMP7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VAMP7 Antibody

Binding Specificity: AA 24-190

Purpose: Anti-SYBL1/VAMP7 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-SYBL1/VAMP7 Antibody Picoband® (ABIN4886758). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human SYBL1 recombinant protein (Position: N24-T190). Human SYBL1 shares 97.6% and 95.2% amino acid (aa) sequence identity with mouse and rat SYBL1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: SYBL1 synaptobrevin-like 1". 2. D'Esposito M, Ciccodicola A, Gianfrancesco F, Esposito T, Flagiello L, Mazzarella R, Schlessinger D, D'Urso M (Jul 1996). "A synaptobrevin-like gene in the Xq28 pseudoautosomal region undergoes X inactivation". Nat. Genet. 13 (2): 227-9. 3. Filippini F, Rossi V, Galli T, Budillon A, D'Urso M, D'Esposito M (Jul 2001). "Longins: a new evolutionary conserved VAMP family sharing a novel SNARE domain". Trends Biochem. Sci. 26 (7): 407-9.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for VAMP7

Target: VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

Alternative Name: VAMP7

Background:

Synonyms: Vesicle-associated membrane protein 7,VAMP-7,Synaptobrevin-like protein 1,Tetanus-insensitive VAMP,Ti-VAMP,VAMP7,SYBL1,

Tissue Specificity: Detected in all tissues tested.

Background: Vesicle-associated membrane protein 7 (VAMP-7), also known as SYBL1, is a protein that in humans is encoded by the VAMP7 gene. This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide- sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.

Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Molecular Weight: 25 kDa

Gene ID: 6845

UniProt: P51809