PRNP antibody

Catalog No. ABIN4889036

The Mouse Monoclonal anti-PRNP antibody is suitable to detect PRNP in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for PRNP antibody (ABIN4889036)

Target: PRNP (Prion Protein (PRNP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PRNP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: EM-20

Product Details anti-PRNP Antibody

Specificity: Reacts with human CD230 / Human Prion Protein (PrP) in its diglycosylated (~40 kDa), monoglycosylated (~30 kDa) as well as non-glycosylated (~20 kDa) forms

Cross-Reactivity (Details): Suitable for discrimination between normal cellular prion protein (PrPc) and its conformationally changed form (PrPSc) prion protein.

Purification: Purified (protein A)

Immunogen: Recombinant human prion protein

Isotype: IgG2a

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(0.5 μg/mL) IHC(10 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, Sodium azide 15 mM

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at +2 +8°C. Do not freeze.

Target Details for PRNP

Target: PRNP (Prion Protein (PRNP))

Alternative Name: CD230

Gene ID: 5621

UniProt: P04156

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation