CST3 antibody

Catalog No. ABIN4901344

This Mouse Monoclonal antibody specifically detects CST3 in WB, ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CST3 antibody (ABIN4901344)

Target: CST3 (Cystatin C (CST3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CST3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 7F11

Product Details anti-CST3 Antibody

Purpose: Cystatin C is a protein encoded by the CST3 gene which is approximately 15,7 kDa. Cystatin C is secreted into the extracellular space. It is involved in the innate immune system, salivary secretion, neuroscience and plaque formation. This protein falls under the cystatin superfamily. It is the most abundant extracellular inhibitor of cysteine proteases and is thought to serve an important physiological role as a local regulator of this enzyme activity. Cystatin C is expressed in the nervous system, blood, kidney, saliva and muscle. Mutations in the CST3 gene may result in Creutzfeldt-Jakob disease. STJ97732 was developed from clone 7F11 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of CST3.

Specificity: Cystatin C Mouse Monoclonal Antibody (7F11) detects endogenous levels of CST3

Characteristics: Mouse Monoclonal to Cystatin C.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Recombinant peptide derived from Cystatin C

Isotype: IgG1

Application Details

Application Notes: WB 1:1000-2000
IHC 1:100-200

Comment:

Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for CST3

Target: CST3 (Cystatin C (CST3))

Alternative Name: Cystatin C

Gene ID: 1471

UniProt: P01034