ITGAL antibody

Catalog No. ABIN490165

This Rat Monoclonal antibody specifically detects ITGAL in FACS, IP, IHC, Func, IHC (fro), BR and Neut. It exhibits reactivity toward Mouse.

Quick Overview for ITGAL antibody (ABIN490165)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGAL antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Neutralization (Neut)

Clone: M17-4

Product Details anti-ITGAL Antibody

Specificity: The rat monoclonal antibody M17/4 reacts with CD11a (alpha-subunit of murine LFA-1), a 180 kD type I transmembrane glycoprotein expressed on B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils.

Purification: Protein G purified

Immunogen: C57BL/6 mouse splenic secondary cytotoxic T lymphocytes.

Isotype: IgG2a

Application Details

Application Notes: Approved: Block, Flo, Func, IHC, IHC-Fr, IP, Neut

Usage: Flow Cytometry: Recommended dilution - 1 μg/mL. Immunohistochemistry (frozen sections): Positive tissue - mouse spleen or thymus. Application note - acetone fixation. Functional Application: Blocking.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: LFA-1 / CD11A

Background: Name/Gene ID: ITGAL
Family: Integrin

Synonyms: ITGAL, CD11A, Integrin alpha-L, LFA-1 alpha, LFA-1A, Integrin gene promoter, Alpha polypeptide), CD11a antigen, LFA-1, LFA1A

Gene ID: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex