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L-Selectin antibody

This Mouse Monoclonal antibody specifically detects L-Selectin in FACS, WB, IHC, IP, IHC (fro), Func, BR and Neut. It exhibits reactivity toward Human.
Catalog No. ABIN490171

Quick Overview for L-Selectin antibody (ABIN490171)

Target

See all L-Selectin (SELL) Antibodies
L-Selectin (SELL) (Selectin L (SELL))

Reactivity

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Human

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This L-Selectin antibody is un-conjugated

Application

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Blocking Reagent (BR), Neutralization (Neut)

Clone

DREG-56
  • Specificity

    The mouse monoclonal antibody DREG56 recognizes CD62L / L-selectin, a 65-76 kD cell surface protein, expressed by neutrophils, monocytes, and subsets of T, B, and NK cells, that interacts with specific carbohydrates exposed on activated endothelial cells. HLDA V, WS Code S056.

    Purification

    Protein A purified

    Immunogen

    PMA-activated human peripheral blood leukocytes.

    Isotype

    IgG1
  • Application Notes

    Approved: Block, Flo, Func, IHC, IHC-Fr, IP, Neut, WB

    Usage: Flow Cytometry: Recommended dilution - 2 μg/mL. Western Blotting: Application note - non-reducing conditions. Functional Application: Particularly effective in blocking of lymphocyte CD62L-mediated binding to peripheral lymph node HEV.

    Not recommended for: IHC-P

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS, 15 mM sodium azide,  pH 7.4

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    avoid freeze thaw cycles.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
  • Target

    L-Selectin (SELL) (Selectin L (SELL))

    Alternative Name

    SELL / L-Selectin / CD62L

    Target Type

    Chemical

    Background

    Name/Gene ID: SELL

    Synonyms: SELL, CD62L, CD62L antigen, LAM-1, LAM1, LECAM1, LEU8, Leukocyte adhesion molecule 1, Lyam-1, LSEL, gp90-MEL, HLHRc, PLNHR, L-selectin, Leu-8, Selectin L, LNHR, LYAM1, Lymph node homing receptor, Lymphocyte adhesion molecule 1, TQ1, Pln homing receptor

    Gene ID

    6402
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