Inhibin alpha antibody
Quick Overview for Inhibin alpha antibody (ABIN4901801)
Target
See all Inhibin alpha (INHA) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Mouse monoclonal to Inhibin α.
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Specificity
- Inhibin α Monoclonal Antibody detects endogenous levels of Inhibin α protein.
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Characteristics
- Mouse Monoclonal to Inhibin α.
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Purification
- Affinity purification
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Immunogen
- Purified recombinant fragment of human Inhibin alpha expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
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WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:10000 -
Comment
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Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female.
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Restrictions
- For Research Use only
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Inhibin alpha (INHA) (Inhibin, alpha (INHA))
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Alternative Name
- Inhibin alpha
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Gene ID
- 3623
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UniProt
- P05111
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Pathways
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
Target
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