PPARD antibody

Catalog No. ABIN4902153

This anti-PPARD antibody is a Mouse Monoclonal antibody detecting PPARD in IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for PPARD antibody (ABIN4902153)

Target: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPARD antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2F9

Product Details anti-PPARD Antibody

Purpose: PPAR delta is a protein encoded by the PPARD gene which is approximately 49,9 kDa. PPAR delta is localised to the nucleus. It is involved in pyruvate metabolism and the citric acid cycle, gene expression, metabolism and nuclear receptor transcription pathway. This protein falls under the peroxisome proliferator-activated receptor family. It is a nuclear hormone receptor that binds peroxisome proliferators and controls the size and number of peroxisomes produced by cells. It may also function as an integrator of transcription repression and nuclear receptor signalling. PPAR delta is ubiquitously expressed with the highest levels in the placenta and skeletal muscle. Mutations in the PPARD gene may result in atherosclerosis. STJ97707 was developed from clone 2F9 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of PPAR delta.

Specificity: PPAR Delta Mouse Monoclonal Antibody (2F9) detects endogenous levels of PPAR Delta

Characteristics: Mouse Monoclonal to PPAR Delta.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Recombinant peptide derived from PPAR Delta

Isotype: IgG1

Application Details

Application Notes: IHC 1:100-200

Comment:

Ubiquitous with maximal levels in placenta and skeletal muscle.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for PPARD

Target: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Alternative Name: PPAR Delta

Gene ID: 5467

UniProt: Q03181

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation