TFF1 antibody (AA 10-50)

Catalog No. ABIN4902183

This anti-TFF1 antibody is a Rabbit Polyclonal antibody detecting TFF1 in ELISA and IHC (p). Suitable for Human.

Quick Overview for TFF1 antibody (AA 10-50) (ABIN4902183)

Target: TFF1 (Trefoil Factor 1 (TFF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFF1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TFF1 Antibody

Binding Specificity: AA 10-50

Purpose: Rabbit polyclonal to pS2.

Specificity: The antibody detects endogenous pS2.

Characteristics: Rabbit Polyclonal to pS2.

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthetic peptide from human pS2 protein.

Isotype: IgG

Application Details

Application Notes: IHC-P 1:50-300
ELISA 1:5000-20000

Comment:

Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the pancreas (at protein level). Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system (at protein level). Detected in urine (at protein level). Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (at protein level).

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS,  pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for TFF1

Target: TFF1 (Trefoil Factor 1 (TFF1))

Alternative Name: pS2

Gene ID: 7031

UniProt: P04155

Pathways: EGFR Signaling Pathway