BAIAP2 antibody

Catalog No. ABIN4906460

The Mouse Monoclonal anti-BAIAP2 antibody has been validated for WB. It is suitable to detect BAIAP2 in samples from Human and Mouse.

Quick Overview for BAIAP2 antibody (ABIN4906460)

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This BAIAP2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 4G7

Product Details anti-BAIAP2 Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged BAIAP2 protein was used to produced this monoclonal antibody.

Isotype: IgG2b

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BAIAP2

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Alternative Name: BAIAP2

Background:

Synonyms: BAP2, FLAF3, IRSP53, Brain-specific angiogenesis inhibitor 1-associated protein 2, BAI-associated protein 2, BAI1-associated protein 2, Protein BAP2, Fas ligand-associated factor 3, Insulin receptor substrate p53/p58, IRS-58, IRSp53/58, Insulin receptor substrate protein of 53 kDa, Insulin receptor substrate p53, BAIAP2

Background: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.

Gene ID: 10458

UniProt: Q9UQB8