CBY1/PGEA1 antibody (AA 51-126) (Cy5)

Catalog No. ABIN4907499

This anti-CBY1/PGEA1 antibody is a Rabbit Polyclonal antibody detecting CBY1/PGEA1 in IF (cc) and IF (p). Suitable for Human.

Quick Overview for CBY1/PGEA1 antibody (AA 51-126) (Cy5) (ABIN4907499)

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBY1/PGEA1 antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CBY1/PGEA1 Antibody (Cy5)

Binding Specificity: AA 51-126

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CBY1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CBY1/PGEA1

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Alternative Name: CBY1

Background:

Synonyms: CBY, arb1, PGEA1, C22orf2, PIGEA14, PIGEA-14, HS508I15A, Protein chibby homolog 1, ARPP-binding protein, Cytosolic leucine-rich protein, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1, CBY1, HRIHFB2025

Background: Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.

Gene ID: 25776

UniProt: Q9Y3M2