CCRK antibody

Catalog No. ABIN4907618

The Mouse Monoclonal anti-CCRK antibody has been validated for WB. It is suitable to detect CCRK in samples from Human.

Quick Overview for CCRK antibody (ABIN4907618)

Target: CCRK (CDK20) (Cyclin-Dependent Kinase 20 (CDK20))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCRK antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 5C1

Product Details anti-CCRK Antibody

Cross-Reactivity: Human

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: Purified His-tagged CCRK protein was used to produced this monoclonal antibody.

Isotype: IgG1

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CCRK

Target: CCRK (CDK20) (Cyclin-Dependent Kinase 20 (CDK20))

Alternative Name: CCRK

Background:

Synonyms: P42, CCRK, CDCH, PNQALRE, Cyclin-dependent kinase 20, CDK-activating kinase p42, CAK-kinase p42, Cell cycle-related kinase, Cell division protein kinase 20, Cyclin-dependent protein kinase H, Cyclin-kinase-activating kinase p42, CDK20

Background: Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.

Gene ID: 23552

UniProt: Q8IZL9