CD43 antibody (AA 101-200) (Biotin)

Catalog No. ABIN4907739

This anti-CD43 antibody is a Rabbit Polyclonal antibody detecting CD43 in WB and ELISA. Suitable for Mouse.

Quick Overview for CD43 antibody (AA 101-200) (Biotin) (ABIN4907739)

Target: CD43 (SPN) (Sialophorin (SPN))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD43 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Product Details anti-CD43 Antibody (Biotin)

Binding Specificity: AA 101-200

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD43

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CD43

Target: CD43 (SPN) (Sialophorin (SPN))

Alternative Name: CD43

Background:

Synonyms: LSN, CD43, GALGP, GPL115, Leukosialin, Galactoglycoprotein, Leukocyte sialoglycoprotein, Sialophorin, SPN

Background: One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity).

Gene ID: 6693

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity