TLE4 antibody

Catalog No. ABIN4914677

The Mouse Monoclonal anti-TLE4 antibody is suitable to detect TLE4 in samples from Human. It has been validated for WB.

Quick Overview for TLE4 antibody (ABIN4914677)

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLE4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 4C4

Product Details anti-TLE4 Antibody

Cross-Reactivity: Human

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This TLE4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human TLE4.

Isotype: IgM

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TLE4

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Alternative Name: TLE4

Background:

Synonyms: ESG, BCE1, ESG4, GRG4, BCE-1, Grg-4, E(spI), Transducin-like enhancer protein 4, Groucho-related protein 4, TLE4, KIAA1261

Background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity).

Gene ID: 7091

UniProt: Q04727

Pathways: WNT Signaling