8-OHDG antibody

Catalog No. ABIN492633

The Mouse Monoclonal anti-8-OHDG antibody (Clone N45-1) (ABIN492633) specifically detects 8-OHDG in IHC (p), EIA and IF.

Quick Overview for 8-OHDG antibody (ABIN492633)

Target: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Host: Mouse

Clonality: Monoclonal

Conjugate: This 8-OHDG antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Clone: N45-1

Product Details anti-8-OHDG Antibody

Characteristics: Synonyms: 8OHdG, 8-OFdG, 8OHG, 8-OHG, 8-Hydroxyguanosine, 8-Hydroxy-2'-deoxyguanosine,8-Hydroxyguanine, 8OG

Purification: Ammnonium Sulphate Precipitation.

Immunogen: 8-OHdG conjugated Keyhole Limpet Hemocyanin

Isotype: IgG1

Application Details

Application Notes: ELISAImmunohistochemistry. See References for more details.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Resuspend in aqua bidest to initial volume

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details for 8-OHDG

Target: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Alternative Name: 8-Hydroxy-Guanosine / 8-OHG

Target Type: Chemical

Background: 8 Hydroxyguanosine (80G) is a modified base which occurs in DNA as a result of oxidative stress. 8 Hydroxy-2'deoxyguanosine (8OHdG) has become a sensitive marker of oxidative damage in cellular DNA and has been reported to be excreted in the urine. Levels of 8OHdG have been shown to increase on exposure to ionizing radiation and tobacco smoke.Synonyms: 8-Hydroxy-2'-deoxyguanosine, 8-Hydroxyguanine, 8-Hydroxyguanosine, 8-OFdG, 8-OHG, 8OG, 8OHG, 8OHdG