AMACR antibody

Catalog No. ABIN4949444

This anti-AMACR antibody is a Mouse Monoclonal antibody detecting AMACR in IF and IHC (p). Suitable for Human.

Quick Overview for AMACR antibody (ABIN4949444)

Target: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AMACR antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AMACR-1723

Product Details anti-AMACR Antibody

Purification: Protein G affinity chromatography

Immunogen: A recombinant human protein was used as the immunogen for the AMACR antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the AMACR antibody should be determined by the researcher.\. Immunohistology (FFPE): 1-2 μg/mL for 30 minutes at RT,IF: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in sterile PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the AMACR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for AMACR

Target: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Alternative Name: AMACR / p504S

Background: AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.

Pathways: Monocarboxylic Acid Catabolic Process