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KRT15 antibody (C-Term)

The Mouse Monoclonal anti-KRT15 antibody has been validated for WB, FACS, IF, IHC (fro) and IHC (p). It is suitable to detect KRT15 in samples from Human, Rat and Cow.
Catalog No. ABIN4949584

Quick Overview for KRT15 antibody (C-Term) (ABIN4949584)

Target

See all KRT15 Antibodies
KRT15 (Keratin 15 (KRT15))

Reactivity

  • 154
  • 47
  • 27
  • 27
  • 2
Human, Rat, Cow

Host

  • 88
  • 71
  • 2
Mouse

Clonality

  • 95
  • 66
Monoclonal

Conjugate

  • 63
  • 19
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KRT15 antibody is un-conjugated

Application

  • 91
  • 91
  • 62
  • 52
  • 42
  • 19
  • 16
  • 14
  • 14
  • 14
  • 13
  • 10
  • 6
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  • 2
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

LHK15
  • Binding Specificity

    • 18
    • 15
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Purification

    Protein G affinity chromatography

    Immunogen

    A 17 amino acid sequence from the C- terminal of human CK15 was used as the immunogen for the Keratin 15 antibody.

    Isotype

    IgG2a kappa
  • Application Notes

    Optimal dilution of the Keratin 15 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,WB: 0.5-1 μg/mL,Immunohistochemistry (FFPE & Frozen): 0.5-1 μg/mL for 30 min at RT

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Preservative

    Azide free

    Storage

    4 °C,-20 °C

    Storage Comment

    Store the Keratin 15 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target

    KRT15 (Keratin 15 (KRT15))

    Alternative Name

    Cytokeratin 15

    Background

    Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.
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