FTL antibody (AA 38-165)

Catalog No. ABIN4949673

Product Details anti-FTL Antibody

Target: FTL (Ferritin, Light Polypeptide (FTL))

Binding Specificity: AA 38-165

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FTL antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Protein G affinity chromatography

Immunogen: Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin Light Chain antibody.

Clone: FTL-1389

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the Ferritin Light Chain antibody should be determined by the researcher.\. FACS: 0.1-0.2 μg/10^6 cells,IF: 0.1-0.2 μg/mL,IHC (FFPE): 0.1-0.2 μg/mL for 30 min at RT

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Ferritin Light Chain antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Alternative Name: Ferritin (light chain) / FTL1 (FTL Products)

Synonyms: NBIA3 antibody, apoferritin antibody, ferritin antibody, fhc antibody, fth antibody, fth1 antibody, fthl6 antibody, ftn-2 antibody, pig15 antibody, plif antibody, FT antibody, Ftl antibody, Ftl-1 antibody, L-ferritin antibody, FTL antibody, Ftl1 antibody, FTL2 antibody, FTD antibody, ferritin light chain antibody, ferritin, heavy polypeptide 1 L homeolog antibody, ferritin light polypeptide 1 antibody, ferritin, light polypeptide antibody, ferritin light-chain antibody, ferritin light chain 1 antibody, FTL antibody, fth1.L antibody, Ftl1 antibody, CpipJ_CPIJ004069 antibody, Ftl antibody

Background: The FTL gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. This gene has multiple pseudogenes.

Although ferritin light chain has no ferroxidase activity, the light chain may be responsible for the electron transfer across the ferritin protein cage. [Wiki]

Pathways: Transition Metal Ion Homeostasis