Pituitary Growth Hormone 20kDa (AA 58-187) antibody

Catalog No. ABIN4949735

This anti- antibody is a Mouse Monoclonal antibody detecting in IHC (p), FACS and IF. Suitable for Human.

Quick Overview for Pituitary Growth Hormone 20kDa (AA 58-187) antibody (ABIN4949735)

Target: Pituitary Growth Hormone 20kDa

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: GH-1371

Product Details

Binding Specificity: AA 58-187

Purification: Protein G affinity chromatography

Immunogen: Amino acids 58-187 from the human protein were used as the immunogen for this Growth Hormone antibody.

Isotype: IgG2b

Application Details

Application Notes: Titration of the Growth Hormone antibody may be needed for optimal performance.\. FACS: 0.5-1 μg/10^6 cells,IF: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Growth Hormone antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details

Target: Pituitary Growth Hormone 20kDa

Alternative Name: Growth Hormone (pituitary)

Background: Growth hormone (GH), also known as somatotropin (or as human growth hormone [hGH or HGH] in its human form), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. It is a type of mitogen which is specific only to certain kinds of cells. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland.

GH is a stress hormone that raises the concentration of glucose and free fatty acids. It also stimulates production of IGF-1.

The major isoform of the human growth hormone is a protein of 191 amino acids and a molecular weight of 22,124 daltons. The structure includes four helices necessary for functional interaction with the GH receptor. It appears that, in structure, GH is evolutionarily homologous to prolactin and chorionic somatomammotropin. [Wiki]

Gene ID: 2688