Recombinant Pituitary Growth Hormone 20kDa (AA 58-187) antibody

Catalog No. ABIN6654365

The Mouse Monoclonal anti-Pituitary Growth Hormone 20kDa antibody (Clone rGH-1450) (ABIN6654365) specifically detects Pituitary Growth Hormone 20kDa in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant Pituitary Growth Hormone 20kDa (AA 58-187) antibody (ABIN6654365)

Target: Pituitary Growth Hormone 20kDa

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RGH-1450

Product Details

Binding Specificity: AA 58-187

Purpose: Recombinant GH Antibody (pituitary) / Growth Hormone

Purification: Protein G affinity chromatography

Immunogen: A human partial recombinant protein corresponding to amino acids 58-187 was used as the immunogen for this recombinant GH antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the recombinant GH antibody to be titered up or down for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant GH antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details

Target: Pituitary Growth Hormone 20kDa

Alternative Name: Growth Hormone (pituitary)

Background: Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

UniProt: P01241