Podoplanin antibody (AA 24-126)

Catalog No. ABIN4949854

The Mouse Monoclonal anti-Podoplanin antibody is suitable to detect Podoplanin in samples from Human. It has been validated for WB, FACS, IF and IHC (p).

Quick Overview for Podoplanin antibody (AA 24-126) (ABIN4949854)

Target: Podoplanin (PDPN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Podoplanin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PDPN-1433

Product Details anti-Podoplanin Antibody

Binding Specificity: AA 24-126

Purification: Protein G affinity chromatography

Immunogen: A human recombinant partial protein corresponding to amino acids 24-126 was used as the immunogen for the Podoplanin antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal dilution of the Podoplanin antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IF: 0.5-1 μg/mL,FACS: 0.5-1 μg/million cells in 0.1ml,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Podoplanin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for Podoplanin

Target: Podoplanin (PDPN)

Alternative Name: Podoplanin / gp36

Background: Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

Pathways: Dicarboxylic Acid Transport