Fatty Acid Synthase antibody (AA 1-226)

Catalog No. ABIN4950995

This anti-Fatty Acid Synthase antibody is a Rabbit Polyclonal antibody detecting Fatty Acid Synthase in WB, ICC and IHC (p). Suitable for Human.

Quick Overview for Fatty Acid Synthase antibody (AA 1-226) (ABIN4950995)

Target: Fatty Acid Synthase (FASN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Fatty Acid Synthase Antibody

Binding Specificity: AA 1-226

Purification: Antigen affinity

Immunogen: Amino acids 1-226 of human FASN were used as the immunogen for the FASN antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the FASN antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ICC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the FASN antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: FASN / Fatty acid synthase

Background: Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene. The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

UniProt: P49327

Pathways: AMPK Signaling