Dnmt2 antibody (AA 201-230)

Catalog No. ABIN3029269

This Rabbit Polyclonal antibody specifically detects Dnmt2 in WB, ELISA and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for Dnmt2 antibody (AA 201-230) (ABIN3029269)

Target: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dnmt2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Dnmt2 Antibody

Binding Specificity: AA 201-230

Purification: Purified

Immunogen: A portion of amino acids 201-230 from the mouse protein was used as the immunogen for this Dnmt2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Dnmt2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C for up to one month. For long term, aliquot the Dnmt2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Dnmt2

Target: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Alternative Name: Dnmt2

Background: Dnmt2 does not appear to be active as a DNA methyltransferase, however, its strong binding to DNA suggests that it may mark specific sequences in the genome by binding to DNA through the specific target-recognizing motif. Dnmt2 is strongly expressed in thymus, testis, and at much lower levels in spleen, lung, brain, heart, kidney, liver, skeletal muscle and embryonic stem cells. This protein belongs to the 5-cystosine methyltransferase family.

UniProt: O55055