EIF4E antibody

Catalog No. ABIN4953242

The Mouse Monoclonal anti-EIF4E antibody (Clone 8C8-C10-C12) (ABIN4953242) specifically detects EIF4E in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for EIF4E antibody (ABIN4953242)

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This EIF4E antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 8C8-C10-C12

Product Details anti-EIF4E Antibody

Purification: Protein G affinity

Immunogen: A human recombinant protein was used as the immunogen for this EIF4E antibody.

Isotype: IgG1

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the EIF4E antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Buffer: Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

Storage: -20 °C

Storage Comment: Store the EIF4E antibody at -20°C.

Target Details for EIF4E

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Alternative Name: EIF4E

Background: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. [UniProt]

UniProt: P06730

Pathways: BCR Signaling