ADA
Reactivity: Mouse, Rat
WB, ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Titration of the ADA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the ADA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
ADA
(Adenosine Deaminase (ADA))
Alternative Name
ADA
Background
This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.