CD13 antibody (AA 156-184)

Catalog No. ABIN3029889

This anti-CD13 antibody is a Mouse Monoclonal antibody detecting CD13 in WB and ELISA. Suitable for Human.

Quick Overview for CD13 antibody (AA 156-184) (ABIN3029889)

Target: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 505CT12-1-2

Product Details anti-CD13 Antibody

Binding Specificity: AA 156-184

Purification: Purified

Immunogen: A portion of amino acids 156-184 from the human protein was used as the immunogen for this ANPEP antibody.

Isotype: IgG2a

Application Details

Application Notes: Titration of the ANPEP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ANPEP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD13

Target: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Alternative Name: ANPEP

Background: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.

UniProt: P15144

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones