FOXP3 antibody (AA 397-423)

Catalog No. ABIN3030997

This Rabbit Polyclonal antibody specifically detects FOXP3 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for FOXP3 antibody (AA 397-423) (ABIN3030997)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FOXP3 Antibody

Binding Specificity: AA 397-423

Cross-Reactivity (Details): Expected species reactivity: Primate

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 397-423 from the human protein was used as the immunogen for this anti-FOXP3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the anti-FOXP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the anti-FOXP3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Alternative Name: FOXP3

Background: Forkhead box P3 is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

UniProt: Q9BZS1

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation