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APOE antibody (AA 263-292)

This anti-APOE antibody is a Rabbit Polyclonal antibody detecting APOE in WB, ELISA and IHC. Suitable for Human.
Catalog No. ABIN3029997

Quick Overview for APOE antibody (AA 263-292) (ABIN3029997)

Target

See all APOE Antibodies
APOE (Apolipoprotein E (APOE))

Reactivity

  • 110
  • 86
  • 74
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Host

  • 123
  • 46
  • 9
  • 2
  • 1
Rabbit

Clonality

  • 121
  • 59
Polyclonal

Conjugate

  • 97
  • 18
  • 11
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This APOE antibody is un-conjugated

Application

  • 145
  • 68
  • 60
  • 47
  • 44
  • 39
  • 39
  • 22
  • 13
  • 12
  • 9
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Binding Specificity

    • 15
    • 15
    • 15
    • 11
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 263-292

    Cross-Reactivity (Details)

    Expected species reactivity: Primate, Rabbit

    Purification

    Antigen affinity purified

    Immunogen

    A portion of amino acids 263-292 from the human protein was used as the immunogen for this ApoE antibody.

    Isotype

    Ig Fraction
  • Application Notes

    Titration of the ApoE antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Aliquot the ApoE antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    APOE (Apolipoprotein E (APOE))

    Alternative Name

    ApoE (Apolipoprotein E)

    Background

    Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

    UniProt

    P02649

    Pathways

    Regulation of Cell Size, Lipid Metabolism
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