BACE1 antibody (AA 476-501)

Catalog No. ABIN3030158

The Rabbit Polyclonal anti-BACE1 antibody has been validated for WB and ELISA. It is suitable to detect BACE1 in samples from Human and Mouse.

Quick Overview for BACE1 antibody (AA 476-501) (ABIN3030158)

Target: BACE1 (Beta-secretase 1 (BACE1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BACE1 Antibody

Binding Specificity: AA 476-501

Cross-Reactivity (Details): Expected species reactivity: Rat, Bovine

Purification: Purified

Immunogen: A portion of amino acids 476-501 from the human protein was used as the immunogen for this BACE antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the BACE antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the BACE antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for BACE1

Target: BACE1 (Beta-secretase 1 (BACE1))

Alternative Name: BACE

Background: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.

UniProt: P56817