CCR8 antibody (AA 290-317)

Catalog No. ABIN3030499

This Rabbit Polyclonal antibody specifically detects CCR8 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for CCR8 antibody (AA 290-317) (ABIN3030499)

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-CCR8 Antibody

Binding Specificity: AA 290-317

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 290-317 from the human protein was used as the immunogen for this CCR8 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CCR8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CCR8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Alternative Name: CCR8

Background: CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.

UniProt: P51685