CD1b antibody (AA 57-85)
Quick Overview for CD1b antibody (AA 57-85) (ABIN3030367)
Target
See all CD1b (CD1B) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 57-85
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 57-85 from the human protein was used as the immunogen for this CD1b antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the CD1b antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the CD1b antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CD1b (CD1B)
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Alternative Name
- CD1b
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Background
- This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq].
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UniProt
- P29016
Target
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