CD43 antibody (AA 230-257)

Catalog No. ABIN3032562

This anti-CD43 antibody is a Mouse Monoclonal antibody detecting CD43 in WB and ELISA. Suitable for Human.

Quick Overview for CD43 antibody (AA 230-257) (ABIN3032562)

Target: CD43 (SPN) (Sialophorin (SPN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD43 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 423CT7-9-2

Product Details anti-CD43 Antibody

Binding Specificity: AA 230-257

Purification: Purified

Immunogen: A portion of amino acids 230-257 from the human protein was used as the immunogen for this CD43 antibody.

Isotype: IgM

Application Details

Application Notes: Titration of the CD43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD43 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD43

Target: CD43 (SPN) (Sialophorin (SPN))

Alternative Name: CD43

Background: One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity) [UniProt]

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity